Genetic variation in ALDH4A1 is associated with muscle health over the lifespan and across species

The influence of genetic variation on the aging process, including the incidence and severity of age-related diseases, is complex. Here, we define the evolutionarily conserved mitochondrial enzyme ALH-6/ALDH4A1 as a predictive biomarker for age-related changes in muscle health by combining Caenorhab...

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Detalles Bibliográficos
Autores principales: Villa, Osvaldo, Stuhr, Nicole L, Yen, Chia-an, Crimmins, Eileen M, Arpawong, Thalida Em, Curran, Sean P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Evolutionary Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106327/
https://www.ncbi.nlm.nih.gov/pubmed/35470798
http://dx.doi.org/10.7554/eLife.74308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106327/
https://www.ncbi.nlm.nih.gov/pubmed/35470798
http://dx.doi.org/10.7554/eLife.74308

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