Inhibition of (Pro)renin Receptor-Mediated Oxidative Stress Alleviates Doxorubicin-Induced Heart Failure

AIM: Clinical utility of doxorubicin (DOX) is limited by its cardiotoxic side effect, and the underlying mechanism still needs to be fully elucidated. This research aimed to examine the role of (pro)renin receptor (PRR) in DOX-induced heart failure (HF) and its underlying mechanism. MAIN METHODS: Sp...

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Detalles Bibliográficos
Autores principales: Du, Xiao-yi, Xiang, Dao-chun, Gao, Ping, Peng, Hua, Liu, Ya-li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106363/
https://www.ncbi.nlm.nih.gov/pubmed/35574363
http://dx.doi.org/10.3389/fonc.2022.874852

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