Selective inhibition of JNK located on mitochondria protects against mitochondrial dysfunction and cell death caused by endoplasmic reticulum stress in mice with LPS-induced ALI/ARDS

Few pharmacological interventions are able to improve the mortality rate of acute lung injury and acute respiratory distress syndrome (ALI/ARDS). The aim of this research was to elucidate whether endoplasmic reticulum (ER) stress and c-Jun-N-terminal kinase (JNK)-mitochondria pathways serve importan...

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Detalles Bibliográficos
Autores principales: Li, Congcong, Ma, Debin, Chen, Yan, Liu, Wei, Jin, Faguang, Bo, Liyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106374/
https://www.ncbi.nlm.nih.gov/pubmed/35514298
http://dx.doi.org/10.3892/ijmm.2022.5141

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