A Systematic Pan-Cancer Analysis of CASP3 as a Potential Target for Immunotherapy

CASP3 is the gene encoding caspase-3, a specific protease that cleaves substrates such as poly-ADP ribose polymerase and acetyl-DEVD-7-amino-4-methylcoumarin. This enzymatic activity leads to DNA fragmentation, which is a hallmark of apoptosis. Although recent studies have demonstrated that CASP3 pl...

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Detalles Bibliográficos
Autores principales: Zhou, Zheng, Xu, Shiying, Jiang, Liehao, Tan, Zhuo, Wang, Jiafeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106394/
https://www.ncbi.nlm.nih.gov/pubmed/35573727
http://dx.doi.org/10.3389/fmolb.2022.776808

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