Safety and immunogenicity of an egg-based inactivated Newcastle disease virus vaccine expressing SARS-CoV-2 spike: Interim results of a randomized, placebo-controlled, phase 1/2 trial in Vietnam

Production of affordable coronavirus disease 2019 (COVID-19) vaccines in low- and middle-income countries is needed. NDV-HXP-S is an inactivated egg-based Newcastle disease virus (NDV) vaccine expressing the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Wuhan-Hu-1. Th...

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Detalles Bibliográficos
Autores principales: Duc Dang, Anh, Dinh Vu, Thiem, Hai Vu, Ha, Thanh Ta, Van, Thi Van Pham, Anh, Thi Ngoc Dang, Mai, Van Le, Be, Huu Duong, Thai, Van Nguyen, Duoc, Lawpoolsri, Saranath, Chinwangso, Pailinrut, McLellan, Jason S., Hsieh, Ching-Lin, Garcia-Sastre, Adolfo, Palese, Peter, Sun, Weina, Martinez, Jose L., Gonzalez-Dominguez, Irene, Slamanig, Stefan, Manuel Carreño, Juan, Tcheou, Johnstone, Krammer, Florian, Raskin, Ariel, Minh Vu, Huong, Cong Tran, Thang, Mai Nguyen, Huong, Mercer, Laina D., Raghunandan, Rama, Lal, Manjari, White, Jessica A., Hjorth, Richard, Innis, Bruce L., Scharf, Rami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106407/
https://www.ncbi.nlm.nih.gov/pubmed/35577631
http://dx.doi.org/10.1016/j.vaccine.2022.04.078

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