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Fructose-1,6-Bisphosphatase 2 Inhibits Oral Squamous Cell Carcinoma Tumorigenesis and Glucose Metabolism via Downregulation of c-Myc

BACKGROUND: Fructose-1,6-bisphosphatase 2 (FBP2), known as a rate-limiting enzyme in gluconeogenesis, is a tumor suppressor downregulated in various cancers. However, the role of FBP2 in oral squamous cell carcinoma (OSCC) remains largely unclear. METHODS: The level of FBP2 in OSCC tissues and match...

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Detalles Bibliográficos
Autores principales:	Wang, Liang, Wang, Jinbing, Shen, Yi, Zheng, Zhiwei, Sun, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106462/ https://www.ncbi.nlm.nih.gov/pubmed/35571245 http://dx.doi.org/10.1155/2022/6766787

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