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CDK1–cyclin-B1-induced kindlin degradation drives focal adhesion disassembly at mitotic entry

The disassembly of integrin-containing focal adhesions (FAs) at mitotic entry is essential for cell rounding, mitotic retraction fibre formation, bipolar spindle positioning and chromosome segregation. The mechanism that drives FA disassembly at mitotic entry is unknown. Here, we show that the CDK1–...

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Detalles Bibliográficos
Autores principales:	Chen, Nan-Peng, Aretz, Jonas, Fässler, Reinhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106588/ https://www.ncbi.nlm.nih.gov/pubmed/35469017 http://dx.doi.org/10.1038/s41556-022-00886-z

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