Structural identification of vasodilator binding sites on the SUR2 subunit

ATP-sensitive potassium channels (K(ATP)), composed of Kir6 and SUR subunits, convert the metabolic status of the cell into electrical signals. Pharmacological activation of SUR2- containing K(ATP) channels by class of small molecule drugs known as K(ATP) openers leads to hyperpolarization of excita...

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Detalles Bibliográficos
Autores principales: Ding, Dian, Wu, Jing-Xiang, Duan, Xinli, Ma, Songling, Lai, Lipeng, Chen, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106677/
https://www.ncbi.nlm.nih.gov/pubmed/35562524
http://dx.doi.org/10.1038/s41467-022-30428-y

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