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Hippocampal acetylcholine modulates stress-related behaviors independent of specific cholinergic inputs

Acetylcholine (ACh) levels are elevated in actively depressed subjects. Conversely, antagonism of either nicotinic or muscarinic ACh receptors can have antidepressant effects in humans and decrease stress-relevant behaviors in rodents. Consistent with a role for ACh in mediating maladaptive response...

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Detalles Bibliográficos
Autores principales: Mineur, Yann S., Mose, Tenna N., Vanopdenbosch, Laura, Etherington, Ian M., Ogbejesi, Chika, Islam, Ashraful, Pineda, Cristiana M., Crouse, Richard B., Zhou, Wenliang, Thompson, David C., Bentham, Matthew, Picciotto, Marina R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106825/
https://www.ncbi.nlm.nih.gov/pubmed/34997190
http://dx.doi.org/10.1038/s41380-021-01404-7

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