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Downregulation of HMGA2 by Small Interfering RNA Affects the Survival, Migration, and Apoptosis of Prostate Cancer Cell Line

Purpose: To investigate the downregulation of high mobility group AT-hook 2 (HMGA2)expression by small interfering RNAs (siRNAs) in PC3 prostate cancer cell line. HMGA2belongs to the non-histone chromatin-binding protein family that serves as a crucial regulator ofgene transcription. The overexpress...

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Detalles Bibliográficos
Autores principales: Khajouee, Shima, Baghbani, Elham, Mohammadi, Ali, Mansoori, Behzad, Shanehbandi, Dariush, Hajiasgharzadeh, Khalil, Baradaran, Behzad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106948/
https://www.ncbi.nlm.nih.gov/pubmed/35620335
http://dx.doi.org/10.34172/apb.2022.039