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Development and validation of a risk score for chest pain with suspected non‐ST‐segment elevation acute coronary syndrome

OBJECTIVE: To investigate a new risk score for acute chest pain with suspected non‐ST‐segment elevation acute coronary syndrome (NSTE‐ACS). METHODS: Patients who suffered from Chest pain and suspected NSTE‐ACS were enrolled as subjects. Predictor variables had been analyzed, and a bootstrap techniqu...

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Autores principales: Ma, Chun‐Peng, Liu, Xiao‐Li, Feng, Jian‐Shuang, Dong, Xue‐Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107085/
https://www.ncbi.nlm.nih.gov/pubmed/34964535
http://dx.doi.org/10.1111/anec.12929
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author Ma, Chun‐Peng
Liu, Xiao‐Li
Feng, Jian‐Shuang
Dong, Xue‐Fei
author_facet Ma, Chun‐Peng
Liu, Xiao‐Li
Feng, Jian‐Shuang
Dong, Xue‐Fei
author_sort Ma, Chun‐Peng
collection PubMed
description OBJECTIVE: To investigate a new risk score for acute chest pain with suspected non‐ST‐segment elevation acute coronary syndrome (NSTE‐ACS). METHODS: Patients who suffered from Chest pain and suspected NSTE‐ACS were enrolled as subjects. Predictor variables had been analyzed, and a bootstrap technique was used to evaluate the internal validity of the model, and external validation had been assessed for a prospective cohort study. RESULTS: Thousand five hundred and sixty‐eight patients had been included in this study. Six predictor variables were found to be significant and were used to develop the model. The C‐statistic of the model was 0.83, and internal validation revealed the stability of the model and the absence of over‐optimism. Patients were given different triage recommendations, and the risk score was prospectively validated. CONCLUSIONS: A risk score may be a suitable method for assessing the risk of major adverse cardiac events and aiding patient triage in emergency departments among patients with suspected NSTE‐ACS.
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spelling pubmed-91070852022-05-19 Development and validation of a risk score for chest pain with suspected non‐ST‐segment elevation acute coronary syndrome Ma, Chun‐Peng Liu, Xiao‐Li Feng, Jian‐Shuang Dong, Xue‐Fei Ann Noninvasive Electrocardiol Original Articles OBJECTIVE: To investigate a new risk score for acute chest pain with suspected non‐ST‐segment elevation acute coronary syndrome (NSTE‐ACS). METHODS: Patients who suffered from Chest pain and suspected NSTE‐ACS were enrolled as subjects. Predictor variables had been analyzed, and a bootstrap technique was used to evaluate the internal validity of the model, and external validation had been assessed for a prospective cohort study. RESULTS: Thousand five hundred and sixty‐eight patients had been included in this study. Six predictor variables were found to be significant and were used to develop the model. The C‐statistic of the model was 0.83, and internal validation revealed the stability of the model and the absence of over‐optimism. Patients were given different triage recommendations, and the risk score was prospectively validated. CONCLUSIONS: A risk score may be a suitable method for assessing the risk of major adverse cardiac events and aiding patient triage in emergency departments among patients with suspected NSTE‐ACS. John Wiley and Sons Inc. 2021-12-29 /pmc/articles/PMC9107085/ /pubmed/34964535 http://dx.doi.org/10.1111/anec.12929 Text en © 2021 The Authors. Annals of Noninvasive Electrocardiology published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Articles
Ma, Chun‐Peng
Liu, Xiao‐Li
Feng, Jian‐Shuang
Dong, Xue‐Fei
Development and validation of a risk score for chest pain with suspected non‐ST‐segment elevation acute coronary syndrome
title Development and validation of a risk score for chest pain with suspected non‐ST‐segment elevation acute coronary syndrome
title_full Development and validation of a risk score for chest pain with suspected non‐ST‐segment elevation acute coronary syndrome
title_fullStr Development and validation of a risk score for chest pain with suspected non‐ST‐segment elevation acute coronary syndrome
title_full_unstemmed Development and validation of a risk score for chest pain with suspected non‐ST‐segment elevation acute coronary syndrome
title_short Development and validation of a risk score for chest pain with suspected non‐ST‐segment elevation acute coronary syndrome
title_sort development and validation of a risk score for chest pain with suspected non‐st‐segment elevation acute coronary syndrome
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107085/
https://www.ncbi.nlm.nih.gov/pubmed/34964535
http://dx.doi.org/10.1111/anec.12929
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