Cargando…
Molecular profiling and clinical implications of patients with acute myeloid leukemia and extramedullary manifestations
BACKGROUND: Extramedullary manifestations (EM) are rare in acute myeloid leukemia (AML) and their impact on clinical outcomes is controversially discussed. METHODS: We retrospectively analyzed a large multi-center cohort of 1583 newly diagnosed AML patients, of whom 225 (14.21%) had EM. RESULTS: AML...
Ejemplares similares
-
Loss-of-Function Mutations of BCOR Are an Independent Marker of Adverse Outcomes in Intensively Treated Patients with Acute Myeloid Leukemia
por: Eckardt, Jan-Niklas, et al.
Publicado: (2021) -
Alterations of cohesin complex genes in acute myeloid leukemia: differential co-mutations, clinical presentation and impact on outcome
por: Eckardt, Jan-Niklas, et al.
Publicado: (2023) -
Mutated IKZF1 is an independent marker of adverse risk in acute myeloid leukemia
por: Eckardt, Jan-Niklas, et al.
Publicado: (2023) -
Lysyl oxidase expression is associated with inferior outcome and Extramedullary disease of acute myeloid leukemia
por: Kunadt, Desiree, et al.
Publicado: (2020) -
UBTF tandem duplications are rare but recurrent alterations in adult AML and associated with younger age, myelodysplasia, and inferior outcome
por: Georgi, Julia-Annabell, et al.
Publicado: (2023)