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RNF7 inhibits apoptosis and sunitinib sensitivity and promotes glycolysis in renal cell carcinoma via the SOCS1/JAK/STAT3 feedback loop

BACKGROUND: RING finger protein 7 (RNF7) is a highly conserved protein that functions as an E3 ubiquitin ligase. RNF7 overexpression is indicated in multiple human cancers, but its role in renal cell carcinoma (RCC) and the mechanisms underlying how it regulates the initiation and progression of RCC...

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Detalles Bibliográficos
Autores principales:	Xiao, Chengwu, Zhang, Wei, Hua, Meimian, Chen, Huan, Yang, Bin, Wang, Ye, Yang, Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107170/ https://www.ncbi.nlm.nih.gov/pubmed/35562668 http://dx.doi.org/10.1186/s11658-022-00337-5

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