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Dynamics of dengue and SARS-COV-2 co-infection in an endemic area of Colombia

Since the COVID-19 outbreak, millions of people have been infected with SARS-CoV-2 around the world. An area of epidemiological relevance is Latin America, tropical regions, due to the distribution of endemic diseases such as chikungunya, dengue (DENV), malaria, Zika virus, where febrile disease abo...

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Autores principales: Acosta-Pérez, Tomás, Rodríguez-Yánez, Tomás, Almanza-Hurtado, Amilkar, Martínez-Ávila, María Cristina, Dueñas-Castell, Carmelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107342/
https://www.ncbi.nlm.nih.gov/pubmed/35568905
http://dx.doi.org/10.1186/s40794-022-00169-3
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author Acosta-Pérez, Tomás
Rodríguez-Yánez, Tomás
Almanza-Hurtado, Amilkar
Martínez-Ávila, María Cristina
Dueñas-Castell, Carmelo
author_facet Acosta-Pérez, Tomás
Rodríguez-Yánez, Tomás
Almanza-Hurtado, Amilkar
Martínez-Ávila, María Cristina
Dueñas-Castell, Carmelo
author_sort Acosta-Pérez, Tomás
collection PubMed
description Since the COVID-19 outbreak, millions of people have been infected with SARS-CoV-2 around the world. An area of epidemiological relevance is Latin America, tropical regions, due to the distribution of endemic diseases such as chikungunya, dengue (DENV), malaria, Zika virus, where febrile disease abounds. The early signs and symptoms of DENV and COVID-19 could be similar, making it a risk that patients may be wrongly diagnosed early during the disease. The problem increases since COVID-19 infection can lead to false positives in DENV screening tests. We present two cases of acute undifferentiated febrile syndrome that were diagnosed with SARS-CoV-2 and DENV co-infection, confirmed by ELISA and RT-PCR for both viral pathogens. The occurrence of simultaneous or overlapped infections can alter the usual clinical course, severity, or outcome of each infection. Therefore, epidemiological surveillance and intensified preparation for those scenarios must be considered, as well as further studies should be done to address cases of co-infection promptly to avoid major complications and fatal outcomes during the current pandemic. Other endemic tropical diseases should not be neglected.
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spelling pubmed-91073422022-05-16 Dynamics of dengue and SARS-COV-2 co-infection in an endemic area of Colombia Acosta-Pérez, Tomás Rodríguez-Yánez, Tomás Almanza-Hurtado, Amilkar Martínez-Ávila, María Cristina Dueñas-Castell, Carmelo Trop Dis Travel Med Vaccines Case Report Since the COVID-19 outbreak, millions of people have been infected with SARS-CoV-2 around the world. An area of epidemiological relevance is Latin America, tropical regions, due to the distribution of endemic diseases such as chikungunya, dengue (DENV), malaria, Zika virus, where febrile disease abounds. The early signs and symptoms of DENV and COVID-19 could be similar, making it a risk that patients may be wrongly diagnosed early during the disease. The problem increases since COVID-19 infection can lead to false positives in DENV screening tests. We present two cases of acute undifferentiated febrile syndrome that were diagnosed with SARS-CoV-2 and DENV co-infection, confirmed by ELISA and RT-PCR for both viral pathogens. The occurrence of simultaneous or overlapped infections can alter the usual clinical course, severity, or outcome of each infection. Therefore, epidemiological surveillance and intensified preparation for those scenarios must be considered, as well as further studies should be done to address cases of co-infection promptly to avoid major complications and fatal outcomes during the current pandemic. Other endemic tropical diseases should not be neglected. BioMed Central 2022-05-15 /pmc/articles/PMC9107342/ /pubmed/35568905 http://dx.doi.org/10.1186/s40794-022-00169-3 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Acosta-Pérez, Tomás
Rodríguez-Yánez, Tomás
Almanza-Hurtado, Amilkar
Martínez-Ávila, María Cristina
Dueñas-Castell, Carmelo
Dynamics of dengue and SARS-COV-2 co-infection in an endemic area of Colombia
title Dynamics of dengue and SARS-COV-2 co-infection in an endemic area of Colombia
title_full Dynamics of dengue and SARS-COV-2 co-infection in an endemic area of Colombia
title_fullStr Dynamics of dengue and SARS-COV-2 co-infection in an endemic area of Colombia
title_full_unstemmed Dynamics of dengue and SARS-COV-2 co-infection in an endemic area of Colombia
title_short Dynamics of dengue and SARS-COV-2 co-infection in an endemic area of Colombia
title_sort dynamics of dengue and sars-cov-2 co-infection in an endemic area of colombia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107342/
https://www.ncbi.nlm.nih.gov/pubmed/35568905
http://dx.doi.org/10.1186/s40794-022-00169-3
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