Heteroplasmic mitochondrial DNA mutations in frontotemporal lobar degeneration

Frontotemporal lobar degeneration (FTLD) is a common cause of young onset dementia and is characterised by focal neuropathology. The reasons for the regional neuronal vulnerability are not known. Mitochondrial mechanisms have been implicated in the pathogenesis of FTLD, raising the possibility that...

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Detalles Bibliográficos
Autores principales: Nie, Yu, Murley, Alexander, Golder, Zoe, Rowe, James B., Allinson, Kieren, Chinnery, Patrick F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107417/
https://www.ncbi.nlm.nih.gov/pubmed/35488929
http://dx.doi.org/10.1007/s00401-022-02423-6

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