microRNA-27a-3p delivered by extracellular vesicles from glioblastoma cells induces M2 macrophage polarization via the EZH1/KDM3A/CTGF axis

Glioblastoma (GBM) cell-derived extracellular vesicles (EVs) have been demonstrated to modulate tumor microenvironment. In the present study, we attempted to discuss the role of hsa-microRNA-27a-3p (miR-27a-3p) delivered by GBM-EVs in M2 macrophage polarization. The isolated GBM-EVs were co-cultured...

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Detalles Bibliográficos
Autores principales: Zhao, Guifang, Yu, Hongquan, Ding, Lijuan, Wang, Weiyao, Wang, Huan, Hu, Yao, Qin, Lingsha, Deng, Guangce, Xie, Buqing, Li, Guofeng, Qi, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107457/
https://www.ncbi.nlm.nih.gov/pubmed/35568721
http://dx.doi.org/10.1038/s41420-022-01035-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107457/
https://www.ncbi.nlm.nih.gov/pubmed/35568721
http://dx.doi.org/10.1038/s41420-022-01035-z

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