m6A methylation mediates LHPP acetylation as a tumour aerobic glycolysis suppressor to improve the prognosis of gastric cancer

LHPP, a histidine phosphatase, has been implicated in tumour progression. However, its role, underlying mechanisms, and prognostic significance in human gastric cancer (GC) are elusive. Here, we obtained GC tissues and corresponding normal tissues from 48 patients and identified LHPP as a downregula...

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Detalles Bibliográficos
Autores principales: Lin, Jian-Xian, Lian, Ning-Zi, Gao, You-Xin, Zheng, Qiao-Ling, Yang, Ying-Hong, Ma, Yu-Bin, Xiu, Zhi-Song, Qiu, Qing-Zhu, Wang, Hua-Gen, Zheng, Chao-Hui, Li, Ping, Xie, Jian-Wei, Lu, Jun, Chen, Qi-Yue, Cao, Long-Long, Lin, Mi, Wang, Jia-Bin, Huang, Chang-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107493/
https://www.ncbi.nlm.nih.gov/pubmed/35568711
http://dx.doi.org/10.1038/s41419-022-04859-w

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