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The kinesin KIF20A promotes progression to castration-resistant prostate cancer through autocrine activation of the androgen receptor
Prostate cancer that recurs following androgen-deprivation therapy is termed castration-resistant, which is incurable and is marked by reactivation of androgen receptor (AR) signaling. KIF20A, a kinesin with unique structural features, is overexpressed in human castration-resistant prostate cancer (...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107495/ https://www.ncbi.nlm.nih.gov/pubmed/35418689 http://dx.doi.org/10.1038/s41388-022-02307-9 |