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Translation of liver stage activity of M5717, a Plasmodium elongation factor 2 inhibitor: from bench to bedside

BACKGROUND: Targeting the asymptomatic liver stage of Plasmodium infection through chemoprevention could become a key intervention to reduce malaria-associated incidence and mortality. METHODS: M5717, a Plasmodium elongation factor 2 inhibitor, was assessed in vitro and in vivo with readily accessib...

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Detalles Bibliográficos
Autores principales:	Khandelwal, Akash, Arez, Francisca, Alves, Paula M., Badolo, Lassina, Brito, Catarina, Fischli, Christoph, Fontinha, Diana, Oeuvray, Claude, Prudêncio, Miguel, Rottmann, Matthias, Wilkins, Justin, Yalkinoglu, Özkan, Bagchus, Wilhelmina M., Spangenberg, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107587/ https://www.ncbi.nlm.nih.gov/pubmed/35570264 http://dx.doi.org/10.1186/s12936-022-04171-0

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