Heat shock protein A4 ablation leads to skeletal muscle myopathy associated with dysregulated autophagy and induced apoptosis

BACKGROUND: Molecular chaperones assist protein folding, facilitate degradation of misfolded polypeptides, and thereby maintain protein homeostasis. Impaired chaperone activity leads to defective protein quality control that is implicated in multiple skeletal muscle diseases. The heat shock protein...

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Detalles Bibliográficos
Autores principales: Elkenani, Manar, Barakat, Amal Z., Held, Torsten, Rodrigues, Daniel Marques, Mobarak, Sherok, Swarnka, Surabhi, Adham, Ibrahim M., Mohamed, Belal A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107738/
https://www.ncbi.nlm.nih.gov/pubmed/35568953
http://dx.doi.org/10.1186/s12967-022-03418-3

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