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The kyphosis–lordosis difference parameter and its utility in understanding the pathogenesis of adolescent idiopathic scoliosis

OBJECTIVE: The relationship of sagittal spinal shape in the pathogenesis of adolescent idiopathic scoliosis (AIS) is recognised. What is not clear is the relationship between the sagittal shape of those without scoliosis and the potential development of AIS, including the greater prevalence in femal...

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Autores principales: Gardner, Adrian, Berryman, Fiona, Pynsent, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107759/
https://www.ncbi.nlm.nih.gov/pubmed/35570316
http://dx.doi.org/10.1186/s13104-022-06067-3
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author Gardner, Adrian
Berryman, Fiona
Pynsent, Paul
author_facet Gardner, Adrian
Berryman, Fiona
Pynsent, Paul
author_sort Gardner, Adrian
collection PubMed
description OBJECTIVE: The relationship of sagittal spinal shape in the pathogenesis of adolescent idiopathic scoliosis (AIS) is recognised. What is not clear is the relationship between the sagittal shape of those without scoliosis and the potential development of AIS, including the greater prevalence in females. The use of a new parameter, the kyphosis–lordosis (KL) difference, was developed to explore this further. RESULTS: The KL difference was calculated for 117 males and 79 females over seven years with 831 measures made. For females, the KL difference, between the ages of 9 and 12 ½ years, decreases from 5° to nearly 0° until starting to climb again from the age of 14 years, back to 5° by the age of 16 ½ years. For males, there is a gradual decline from 9° at age 9 years to 5° at age 17 years. Both age and sex were statistically significant in the development of the parameter. When comparing to previously published data around the true, de-rotated, sagittal shape of the scoliotic spine, the KL difference has utility in explaining the female predominance in the prevalence of AIS. This adds to the weight of evidence behind understanding why AIS develops.
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spelling pubmed-91077592022-05-16 The kyphosis–lordosis difference parameter and its utility in understanding the pathogenesis of adolescent idiopathic scoliosis Gardner, Adrian Berryman, Fiona Pynsent, Paul BMC Res Notes Research Note OBJECTIVE: The relationship of sagittal spinal shape in the pathogenesis of adolescent idiopathic scoliosis (AIS) is recognised. What is not clear is the relationship between the sagittal shape of those without scoliosis and the potential development of AIS, including the greater prevalence in females. The use of a new parameter, the kyphosis–lordosis (KL) difference, was developed to explore this further. RESULTS: The KL difference was calculated for 117 males and 79 females over seven years with 831 measures made. For females, the KL difference, between the ages of 9 and 12 ½ years, decreases from 5° to nearly 0° until starting to climb again from the age of 14 years, back to 5° by the age of 16 ½ years. For males, there is a gradual decline from 9° at age 9 years to 5° at age 17 years. Both age and sex were statistically significant in the development of the parameter. When comparing to previously published data around the true, de-rotated, sagittal shape of the scoliotic spine, the KL difference has utility in explaining the female predominance in the prevalence of AIS. This adds to the weight of evidence behind understanding why AIS develops. BioMed Central 2022-05-15 /pmc/articles/PMC9107759/ /pubmed/35570316 http://dx.doi.org/10.1186/s13104-022-06067-3 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Note
Gardner, Adrian
Berryman, Fiona
Pynsent, Paul
The kyphosis–lordosis difference parameter and its utility in understanding the pathogenesis of adolescent idiopathic scoliosis
title The kyphosis–lordosis difference parameter and its utility in understanding the pathogenesis of adolescent idiopathic scoliosis
title_full The kyphosis–lordosis difference parameter and its utility in understanding the pathogenesis of adolescent idiopathic scoliosis
title_fullStr The kyphosis–lordosis difference parameter and its utility in understanding the pathogenesis of adolescent idiopathic scoliosis
title_full_unstemmed The kyphosis–lordosis difference parameter and its utility in understanding the pathogenesis of adolescent idiopathic scoliosis
title_short The kyphosis–lordosis difference parameter and its utility in understanding the pathogenesis of adolescent idiopathic scoliosis
title_sort kyphosis–lordosis difference parameter and its utility in understanding the pathogenesis of adolescent idiopathic scoliosis
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107759/
https://www.ncbi.nlm.nih.gov/pubmed/35570316
http://dx.doi.org/10.1186/s13104-022-06067-3
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