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Cardiovascular Complication following Covishield Vaccination in Nepal: A Case Report

Nepal started the COVID-19 vaccination on 27 January 2021 with AstraZeneca/Oxford Coronavirus Disease-19 AZD1222 (Covishield) vaccine to control the Coronavirus disease pandemic. The vaccine has a good safety profile, with cardiovascular complications being rare. Herein we report a rare case of card...

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Autores principales: Basnet, Angela, Ojha, Shiva Kumar, Jha, Suman Kumar, Paudyal, Anjana, Khadka, Manoj, Khadka, Manita, Shrestha, Dhan Bahadur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of the Nepal Medical Association 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107837/
https://www.ncbi.nlm.nih.gov/pubmed/34508485
http://dx.doi.org/10.31729/jnma.6454
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author Basnet, Angela
Ojha, Shiva Kumar
Jha, Suman Kumar
Paudyal, Anjana
Khadka, Manoj
Khadka, Manita
Shrestha, Dhan Bahadur
author_facet Basnet, Angela
Ojha, Shiva Kumar
Jha, Suman Kumar
Paudyal, Anjana
Khadka, Manoj
Khadka, Manita
Shrestha, Dhan Bahadur
author_sort Basnet, Angela
collection PubMed
description Nepal started the COVID-19 vaccination on 27 January 2021 with AstraZeneca/Oxford Coronavirus Disease-19 AZD1222 (Covishield) vaccine to control the Coronavirus disease pandemic. The vaccine has a good safety profile, with cardiovascular complications being rare. Herein we report a rare case of cardiovascular complication following Covishield vaccination in a 33 years old female who had dizziness and elevated blood pressure immediately following vaccination and abnormal electrocardiogram showing T wave inversions followed by left bundle branch block. The patient was kept on observation, following which the blood pressure and electrocardiogram changes were normal by seven days. This cardiovascular complication following the vaccination demands further investigation into the adverse event of the vaccine. However, since the benefit of the vaccine outweighs the risk, World Health Organization has recommended the continuity of the vaccine as of now.
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spelling pubmed-91078372022-05-27 Cardiovascular Complication following Covishield Vaccination in Nepal: A Case Report Basnet, Angela Ojha, Shiva Kumar Jha, Suman Kumar Paudyal, Anjana Khadka, Manoj Khadka, Manita Shrestha, Dhan Bahadur JNMA J Nepal Med Assoc Case Report Nepal started the COVID-19 vaccination on 27 January 2021 with AstraZeneca/Oxford Coronavirus Disease-19 AZD1222 (Covishield) vaccine to control the Coronavirus disease pandemic. The vaccine has a good safety profile, with cardiovascular complications being rare. Herein we report a rare case of cardiovascular complication following Covishield vaccination in a 33 years old female who had dizziness and elevated blood pressure immediately following vaccination and abnormal electrocardiogram showing T wave inversions followed by left bundle branch block. The patient was kept on observation, following which the blood pressure and electrocardiogram changes were normal by seven days. This cardiovascular complication following the vaccination demands further investigation into the adverse event of the vaccine. However, since the benefit of the vaccine outweighs the risk, World Health Organization has recommended the continuity of the vaccine as of now. Journal of the Nepal Medical Association 2021-08 2021-08-31 /pmc/articles/PMC9107837/ /pubmed/34508485 http://dx.doi.org/10.31729/jnma.6454 Text en © The Author(s) 2018. https://creativecommons.org/licenses/by/4.0/This is an Open-Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Basnet, Angela
Ojha, Shiva Kumar
Jha, Suman Kumar
Paudyal, Anjana
Khadka, Manoj
Khadka, Manita
Shrestha, Dhan Bahadur
Cardiovascular Complication following Covishield Vaccination in Nepal: A Case Report
title Cardiovascular Complication following Covishield Vaccination in Nepal: A Case Report
title_full Cardiovascular Complication following Covishield Vaccination in Nepal: A Case Report
title_fullStr Cardiovascular Complication following Covishield Vaccination in Nepal: A Case Report
title_full_unstemmed Cardiovascular Complication following Covishield Vaccination in Nepal: A Case Report
title_short Cardiovascular Complication following Covishield Vaccination in Nepal: A Case Report
title_sort cardiovascular complication following covishield vaccination in nepal: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107837/
https://www.ncbi.nlm.nih.gov/pubmed/34508485
http://dx.doi.org/10.31729/jnma.6454
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