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Metronidazole Induced Cerebellar Toxicity: A Case Report

Metronidazole is a widely used antibiotic against bacteria! and protozoan infections. Even though the therapeutic use of the drug is high, it is associated with some severe side effects like neurotoxicity such as optic neuropathy, peripheral neuropathy, encephalopathy and cerebellar toxicity. We pre...

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Detalles Bibliográficos
Autores principales: Sapkota, Shova, Niroula, Aliska, Prajapati, Rina, Sharma, Subhani, Dhungana, Krishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of the Nepal Medical Association 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107893/
https://www.ncbi.nlm.nih.gov/pubmed/35199725
http://dx.doi.org/10.31729/jnma.6644
Descripción
Sumario:Metronidazole is a widely used antibiotic against bacteria! and protozoan infections. Even though the therapeutic use of the drug is high, it is associated with some severe side effects like neurotoxicity such as optic neuropathy, peripheral neuropathy, encephalopathy and cerebellar toxicity. We present a case of a 55-years male presented with dysarthria, who had positive cerebellar sign and magnetic resonance imaging findings suggestive of metronidazole induced cerebellar toxicity following metronidazole therapy for two months in a case of liver abscess. And, the symptoms resolved after cessation of metronidazole.