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Metronidazole Induced Cerebellar Toxicity: A Case Report

Metronidazole is a widely used antibiotic against bacteria! and protozoan infections. Even though the therapeutic use of the drug is high, it is associated with some severe side effects like neurotoxicity such as optic neuropathy, peripheral neuropathy, encephalopathy and cerebellar toxicity. We pre...

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Autores principales: Sapkota, Shova, Niroula, Aliska, Prajapati, Rina, Sharma, Subhani, Dhungana, Krishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of the Nepal Medical Association 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107893/
https://www.ncbi.nlm.nih.gov/pubmed/35199725
http://dx.doi.org/10.31729/jnma.6644
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author Sapkota, Shova
Niroula, Aliska
Prajapati, Rina
Sharma, Subhani
Dhungana, Krishna
author_facet Sapkota, Shova
Niroula, Aliska
Prajapati, Rina
Sharma, Subhani
Dhungana, Krishna
author_sort Sapkota, Shova
collection PubMed
description Metronidazole is a widely used antibiotic against bacteria! and protozoan infections. Even though the therapeutic use of the drug is high, it is associated with some severe side effects like neurotoxicity such as optic neuropathy, peripheral neuropathy, encephalopathy and cerebellar toxicity. We present a case of a 55-years male presented with dysarthria, who had positive cerebellar sign and magnetic resonance imaging findings suggestive of metronidazole induced cerebellar toxicity following metronidazole therapy for two months in a case of liver abscess. And, the symptoms resolved after cessation of metronidazole.
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spelling pubmed-91078932022-05-27 Metronidazole Induced Cerebellar Toxicity: A Case Report Sapkota, Shova Niroula, Aliska Prajapati, Rina Sharma, Subhani Dhungana, Krishna JNMA J Nepal Med Assoc Case Report Metronidazole is a widely used antibiotic against bacteria! and protozoan infections. Even though the therapeutic use of the drug is high, it is associated with some severe side effects like neurotoxicity such as optic neuropathy, peripheral neuropathy, encephalopathy and cerebellar toxicity. We present a case of a 55-years male presented with dysarthria, who had positive cerebellar sign and magnetic resonance imaging findings suggestive of metronidazole induced cerebellar toxicity following metronidazole therapy for two months in a case of liver abscess. And, the symptoms resolved after cessation of metronidazole. Journal of the Nepal Medical Association 2021-09 2021-09-30 /pmc/articles/PMC9107893/ /pubmed/35199725 http://dx.doi.org/10.31729/jnma.6644 Text en © The Author(s) 2018. https://creativecommons.org/licenses/by/4.0/This is an Open-Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Sapkota, Shova
Niroula, Aliska
Prajapati, Rina
Sharma, Subhani
Dhungana, Krishna
Metronidazole Induced Cerebellar Toxicity: A Case Report
title Metronidazole Induced Cerebellar Toxicity: A Case Report
title_full Metronidazole Induced Cerebellar Toxicity: A Case Report
title_fullStr Metronidazole Induced Cerebellar Toxicity: A Case Report
title_full_unstemmed Metronidazole Induced Cerebellar Toxicity: A Case Report
title_short Metronidazole Induced Cerebellar Toxicity: A Case Report
title_sort metronidazole induced cerebellar toxicity: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107893/
https://www.ncbi.nlm.nih.gov/pubmed/35199725
http://dx.doi.org/10.31729/jnma.6644
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