Ultrapotent and broad neutralization of SARS-CoV-2 variants by modular, tetravalent, bi-paratopic antibodies

Neutralizing antibodies (nAbs) that target the SARS-CoV-2 spike protein have received emergency use approval for treatment of COVID-19. However, with the emergence of variants of concern, there is a need for new treatment options. We report a format that enables modular assembly of bi-paratopic tetr...

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Detalles Bibliográficos
Autores principales: Miersch, Shane, Sharma, Nitin, Saberianfar, Reza, Chen, Chao, Caccuri, Francesca, Zani, Alberto, Caruso, Arnaldo, Case, James Brett, Diamond, Michael S., Amarasinghe, Gaya K., Novelli, Giuseppe, Sidhu, Sachdev S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108025/
https://www.ncbi.nlm.nih.gov/pubmed/35617963
http://dx.doi.org/10.1016/j.celrep.2022.110905

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108025/
https://www.ncbi.nlm.nih.gov/pubmed/35617963
http://dx.doi.org/10.1016/j.celrep.2022.110905

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