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Mubritinib enhanced the inhibiting function of cisplatin in lung cancer by interfering with mitochondrial function

BACKGROUND: Lung cancer is one of the most lethal cancers worldwide. Cisplatin, a widely used anti‐lung cancer drug, has been limited in clinical application due to its drug resistance. Medicines targeting mitochondrial electron transport chain (ETC) complexes may be effective candidates for cisplat...

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Detalles Bibliográficos
Autores principales: Dong, Jingyao, Zhu, Dongshan, Chen, Mengmeng, Wang, Taiwei, Gao, Yan, Liu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108040/
https://www.ncbi.nlm.nih.gov/pubmed/35429141
http://dx.doi.org/10.1111/1759-7714.14425