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Impact of losing adipose tissue on outcomes from PD‐1/PD‐L1 inhibitor monotherapy in non‐small cell lung cancer
BACKGROUND: Adipose tissue induces inflammation, which desensitizes the efficacy of immunotherapy. However, several reports show that the therapeutic effect of programed cell death 1 (PD‐1)/programed death‐ligand 1 (PD‐L1) inhibitor(s) monotherapy is significantly better in obese patients. Therefore...
Autores principales: | Nishioka, Naoya, Naito, Tateaki, Miyawaki, Taichi, Yabe, Michitoshi, Doshita, Kosei, Kodama, Hiroaki, Miyawaki, Eriko, Iida, Yuko, Mamesaya, Nobuaki, Kobayashi, Haruki, Omori, Shota, Ko, Ryo, Wakuda, Kazushige, Ono, Akira, Kenmotsu, Hirotsugu, Murakami, Haruyasu, Takayama, Koichi, Takahashi, Toshiaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons Australia, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108048/ https://www.ncbi.nlm.nih.gov/pubmed/35420262 http://dx.doi.org/10.1111/1759-7714.14421 |
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