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Upregulation of tRNA-Ser-AGA-2-1 Promotes Malignant Behavior in Normal Bronchial Cells

Serine tRNAs (tRNA(Ser)) are frequently overexpressed in tumors and associated with poor prognosis and increased risk of recurrence in breast cancer. Impairment of tRNA biogenesis and abundance also impacts proteome homeostasis, and activates protein quality control systems. Herein, we aimed at test...

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Detalles Bibliográficos
Autores principales:	Santos, Mafalda, Fidalgo, Ana, Varanda, Ana Sofia, Soares, Ana Raquel, Almeida, Gabriela M., Martins, Diana, Mendes, Nuno, Oliveira, Carla, Santos, Manuel A. S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108184/ https://www.ncbi.nlm.nih.gov/pubmed/35586191 http://dx.doi.org/10.3389/fmolb.2022.809985

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