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PCSK9 Contributes to the Cholesterol, Glucose, and Insulin2 Homeostasis in Seminiferous Tubules and Maintenance of Immunotolerance in Testis

The PCSK9 contribution to cholesterol and immunotolerance homeostasis and response to glucose, and insulin in testis and hypophysis were studied using Pcsk9-deficient ((−/−)) and transgenic [Tg (PCSK9)] mice, and diabetic, obese ob/ob and db/db mice. The spermatids/spermatozoa acrosome, peritubular...

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Detalles Bibliográficos
Autores principales:	Pelletier, R.-Marc, Layeghkhavidaki, Hamed, Seidah, Nabil G., Prat, Annik, Vitale, María L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108277/ https://www.ncbi.nlm.nih.gov/pubmed/35586340 http://dx.doi.org/10.3389/fcell.2022.889972

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