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Cancer suppression and the evolution of multiple retrogene copies of TP53 in elephants: A re‐evaluation
Evolving to become bigger and/or longer lived should increase cancer susceptibility, but this predicted increase is not observed, a contradiction named Peto's paradox. A solution is that cancer suppression evolves to minimize cancer susceptibility, and the discovery of 19 retrogene (RTG) copies...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley and Sons Inc.
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108310/ https://www.ncbi.nlm.nih.gov/pubmed/35603034 http://dx.doi.org/10.1111/eva.13383 |