Profilin 1 Induces Tumor Metastasis by Promoting Microvesicle Secretion Through the ROCK 1/p-MLC Pathway in Non-Small Cell Lung Cancer

Profilin 1 (PFN1), an actin-binding protein, plays contrasting roles in the metastasis of several cancers; however, its role in non-small cell lung cancer (NSCLC) metastasis remains unclear. Here, PFN1 expression was upregulated in metastatic NSCLC tissues. PFN1 overexpression significantly promotes...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Ya, Lu, Yichen, Wan, Rongjun, Wang, Yang, Zhang, Chunfang, Li, Min, Deng, Pengbo, Cao, Liming, Hu, Chengping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108340/
https://www.ncbi.nlm.nih.gov/pubmed/35586060
http://dx.doi.org/10.3389/fphar.2022.890891

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108340/
https://www.ncbi.nlm.nih.gov/pubmed/35586060
http://dx.doi.org/10.3389/fphar.2022.890891

Ejemplares similares