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An in silico Model of T Cell Infiltration Dynamics Based on an Advanced in vitro System to Enhance Preclinical Decision Making in Cancer Immunotherapy

Cancer immunotherapy often involves the use of engineered molecules to selectively bind and activate T cells located within tumour tissue. Fundamental to the success of such treatments is the presence or recruitment of T cells localised within the tumour microenvironment. Advanced organ-on-a-chip sy...

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Detalles Bibliográficos
Autores principales:	Lewin, Thomas D., Avignon, Blandine, Tovaglieri, Alessio, Cabon, Lauriane, Gjorevski, Nikolche, Hutchinson, Lucy G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108393/ https://www.ncbi.nlm.nih.gov/pubmed/35586042 http://dx.doi.org/10.3389/fphar.2022.837261

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