Cargando…

Effects of Dexmedetomidine on Immune Cells: A Narrative Review

As we all know, dexmedetomidine (DEX), as a highly selective α(2) adrenergic receptor agonist, exerts sedative, anti-anxiety and hypnotic effects by inhibiting the discharge of norepinephrine neurons in locus coeruleus and GABA-related hypnotic pathways. However, the role of DEX in anti-inflammatory...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Rui, Sun, Yan, Lv, Jing, Dou, Xiaoke, Dai, Maosha, Sun, Shujun, Lin, Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108424/ https://www.ncbi.nlm.nih.gov/pubmed/35586059 http://dx.doi.org/10.3389/fphar.2022.829951

Ejemplares similares

Efficacy and safety evaluation of dexmedetomidine for postoperative patient controlled intravenous analgesia: A systematic review and meta-analysis
por: Chen, Rui, et al.
Publicado: (2022)

The potential role of T-cell metabolism-related molecules in chronic neuropathic pain after nerve injury: a narrative review
por: Dou, Xiaoke, et al.
Publicado: (2023)

Amelioration of myocardial ischemia/reperfusion injury in diabetes: A narrative review of the mechanisms and clinical applications of dexmedetomidine
por: Sun, Meng, et al.
Publicado: (2022)

EGCG protects the mouse brain against cerebral ischemia/reperfusion injury by suppressing autophagy via the AKT/AMPK/mTOR phosphorylation pathway
por: Wang, Li, et al.
Publicado: (2022)

The Protective Effect and Mechanism of Dexmedetomidine on Diabetic Peripheral Neuropathy in Rats
por: Zhang, Yan-zhuo, et al.
Publicado: (2020)

The neuroprotective effect of dexmedetomidine and its mechanism
por: Hu, Yijun, et al.
Publicado: (2022)

Effect of Different Doses of Intrathecal Dexmedetomidine as an Adjuvant Combined With Hyperbaric Ropivacaine in Patients Undergoing Cesarean Section
por: Bi, Yong-hong, et al.
Publicado: (2020)

Combination of Dexmedetomidine and Tramadol in Patient-Controlled Intravenous Analgesia Strengthens Sedative Effect in Pregnancy-Induced Hypertension
por: Zhang, Shu-Yao, et al.
Publicado: (2021)

Pharmacokinetics of Intranasally Administered Dexmedetomidine in Chinese Children
por: Wang, Cheng-Yu, et al.
Publicado: (2019)

Effect of dexmedetomidine on liver transplantation: a meta-analysis
por: Jia, Degong, et al.
Publicado: (2023)

The Efficacy and Safety of Remimazolam Tosilate Versus Dexmedetomidine in Outpatients Undergoing Flexible Bronchoscopy: A Prospective, Randomized, Blind, Non-Inferiority Trial
por: Chen, Xingfang, et al.
Publicado: (2022)

Sugammadex, the Guardian of Deep Muscle Relaxation During Conventional and Robot-Assisted Laparoscopic Surgery: A Narrative Review
por: Sun, Yan, et al.
Publicado: (2021)

Efficacy of dexmedetomidine versus midazolam when combined with butorphanol for sedation and analgesia during burn dressing changes: A randomized clinical trial
por: Ding, Xianchao, et al.
Publicado: (2022)

Dexmedetomidine Improves Postoperative Patient-Controlled Analgesia following Radical Mastectomy
por: Fan, Wei, et al.
Publicado: (2017)

A Comparison of Intranasal Dexmedetomidine, Esketamine or a Dexmedetomidine-Esketamine Combination for Induction of Anaesthesia in Children: A Randomized Controlled Double-Blind Trial
por: Lu, Xinlei, et al.
Publicado: (2022)

Targeting hypoxia-inducible factors for breast cancer therapy: A narrative review
por: Luo, Shuang, et al.
Publicado: (2022)

Analgesic Effects and Safety of Dexmedetomidine Added to Nalbuphine or Sufentanil Patient-Controlled Intravenous Analgesia for Children After Tonsillectomy Adenoidectomy
por: Jia, Yingping, et al.
Publicado: (2022)

The Medicinal Plant Pair Bupleurum chinense-Scutellaria baicalensis – Metabolomics and Metallomics Analysis in a Model for Alcoholic Liver Injury
por: Dang, Zefang, et al.
Publicado: (2019)

γδ T Cell in Cerebral Ischemic Stroke: Characteristic, Immunity-Inflammatory Role, and Therapy
por: Wang, Li, et al.
Publicado: (2022)

The Effects of Different Doses of Alfentanil and Dexmedetomidine on Prevention of Emergence Agitation in Pediatric Tonsillectomy and Adenoidectomy Surgery
por: Zhang, Yan-zhuo, et al.
Publicado: (2022)

Effects of Three Different Doses of Dexmedetomidine and Ropivacaine on Analgesia and the Stress Response in Hypospadias Surgery: A Randomized Trial
por: Wang, Yuan, et al.
Publicado: (2021)

Potential effects of cannabinoids on audiovestibular function: A narrative review
por: Guerra, Joaquin, et al.
Publicado: (2022)

The Protective Effect of Dexmedetomidine Against Ischemia-Reperfusion Injury after Hepatectomy: A Meta-Analysis of Randomized Controlled Trials
por: Huang, Ya-Qun, et al.
Publicado: (2021)

Perioperative utility of amisulpride and dopamine receptor antagonist antiemetics-a narrative review
por: Elias, Murad, et al.
Publicado: (2023)

An intravenous anesthetic drug-propofol, influences the biological characteristics of malignant tumors and reshapes the tumor microenvironment: A narrative literature review
por: Zhou, Xueliang, et al.
Publicado: (2022)

Comparison of the Effects of Oral Midazolam and Intranasal Dexmedetomidine on Preoperative Sedation and Anesthesia Induction in Children Undergoing Surgeries
por: Cai, Yu-Hang, et al.
Publicado: (2021)

RNA-sequencing approach for exploring the protective mechanisms of dexmedetomidine on pancreatic injury in severe acute pancreatitis
por: Yao, Jiaqi, et al.
Publicado: (2023)

Dexmedetomidine Versus Propofol for Patients With Sepsis Requiring Mechanical Ventilation: A Systematic Review and Meta-Analysis
por: Huang, Po, et al.
Publicado: (2021)

Neuroprotective effect of dexmedetomidine on autophagy in mice administered intracerebroventricular injections of Aβ(25–35)
por: Lee, Youn Young, et al.
Publicado: (2023)

D-Amphetamine Rapidly Reverses Dexmedetomidine-Induced Unconsciousness in Rats
por: Kato, Risako, et al.
Publicado: (2021)

Perioperative Low Dose Dexmedetomidine and Its Effect on the Visibility of the Surgical Field for Middle Ear Microsurgery: A Randomised Controlled Trial
por: Wu, Jinhong, et al.
Publicado: (2022)

Mechanisms of the Rapid Effects of Ketamine on Depression and Sleep Disturbances: A Narrative Review
por: Song, Bijia, et al.
Publicado: (2021)

Dexmedetomidine: What’s New for Pediatrics? A Narrative Review
por: Mahmoud, Mohamed, et al.
Publicado: (2020)

Dexmedetomidine in the Treatment of Depression: An Up-to-date Narrative Review
por: Al-Mahrouqi, Tamadhir, et al.
Publicado: (2023)

The Opioid-Sparing Effect of Perioperative Dexmedetomidine Plus Sufentanil Infusion during Neurosurgery: A Retrospective Study
por: Su, Shiyu, et al.
Publicado: (2016)

Mechanism Underlying Acupuncture Therapy in Spinal Cord Injury: A Narrative Overview of Preclinical Studies
por: Jiang, Kunpeng, et al.
Publicado: (2022)

Dexmedetomidine Protects Human Cardiomyocytes Against Ischemia-Reperfusion Injury Through α2-Adrenergic Receptor/AMPK-Dependent Autophagy
por: Xiao, Yingying, et al.
Publicado: (2021)

Effects of Dexmedetomidine on Postoperative Delirium and Expression of IL-1β, IL-6, and TNF-α in Elderly Patients After Hip Fracture Operation
por: Zhang, Wenchao, et al.
Publicado: (2020)

Safety, Pharmacokinetics/Pharmacodynamics, and Absolute Bioavailability of Dexmedetomidine Hydrochloride Nasal Spray in Healthy Subjects: A Randomized, Parallel, Escalating Dose Study
por: Kuang, Yun, et al.
Publicado: (2022)

The Role of Dexmedetomidine in Tumor-Progressive Factors in the Perioperative Period and Cancer Recurrence: A Narrative Review
por: Cai, Qiang, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_635vjrqm1jkujoa7hpskol5uuq