Bryostatin Placebo-Controlled Trials Indicate Cognitive Restoration Above Baseline for Advanced Alzheimer’s Disease in the Absence of Memantine(1)

BACKGROUND: In pre-clinical studies of Alzheimer’s disease (AD) transgenic mice, bryostatin restored synaptic connections, prevented neuronal death, reduced amyloid plaques, and reduced neurofibrillary tangles. OBJECTIVE: Within pre-specified cohorts of advanced AD patients in two double-blind place...

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Detalles Bibliográficos
Autores principales: Thompson, Richard E., Tuchman, Alan J., Alkon, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108553/
https://www.ncbi.nlm.nih.gov/pubmed/35124654
http://dx.doi.org/10.3233/JAD-215545

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