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Efficacy and Safety of Opicapone for Motor Fluctuations as an Adjuvant to Levodopa Therapy in Patients with Parkinson’s Disease: A Systematic Review and Meta-Analysis

BACKGROUND: Long-term levodopa administration for treating Parkinson’s disease (PD) may shorten the duration of effect and cause dyskinesias, inducing the need for catechol-O-methyltransferase (COMT) inhibitors as adjuvant therapy. OBJECTIVE: We provide pooled scientific evidence highlighting the ef...

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Detalles Bibliográficos
Autores principales: Kwak, Nayoung, Park, Jinyoung, Kang, Hye-Young, Lee, Myung-Jun, Suh, Jae Kyung, Lee, Hankil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108568/
https://www.ncbi.nlm.nih.gov/pubmed/35180134
http://dx.doi.org/10.3233/JPD-213057