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Reconsideration of Alzheimer’s Disease Therapy from a Viewpoint of Amyloidogenic Evolvability

 Presuming that Alzheimer’s disease (AD) might represent an antagonistic pleiotropic phenomenon derived from the evolvability of multiple amyloidogenic proteins, targeting such proteins simultaneously could enhance therapeutic efficacy. Furthermore, considering that amyloid-β (Aβ) immunotherapies du...

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Detalles Bibliográficos
Autores principales: Ho, Gilbert, Choo, Pei Chen, Waragai, Masaaki, Inoue, Satoshi, Masliah, Eliezer, Hashimoto, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108623/
https://www.ncbi.nlm.nih.gov/pubmed/35591950
http://dx.doi.org/10.3233/ADR-210021

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