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Reconsideration of Alzheimer’s Disease Therapy from a Viewpoint of Amyloidogenic Evolvability
Presuming that Alzheimer’s disease (AD) might represent an antagonistic pleiotropic phenomenon derived from the evolvability of multiple amyloidogenic proteins, targeting such proteins simultaneously could enhance therapeutic efficacy. Furthermore, considering that amyloid-β (Aβ) immunotherapies du...
Autores principales: | Ho, Gilbert, Choo, Pei Chen, Waragai, Masaaki, Inoue, Satoshi, Masliah, Eliezer, Hashimoto, Makoto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108623/ https://www.ncbi.nlm.nih.gov/pubmed/35591950 http://dx.doi.org/10.3233/ADR-210021 |
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