Cargando…
“Drug‐Carrier” Synergy Therapy for Amyloid‐β Clearance and Inhibition of Tau Phosphorylation via Biomimetic Lipid Nanocomposite Assembly
Amyloid‐β (Aβ) toxicity is considered to be companioned by Tau phosphorylation in Alzheimer's disease (AD). The clinical AD therapy is usually subjected to low blood‐brain barrier (BBB) penetration and complex interaction mechanisms between Aβ and phosphorylated Tau. A “Drug‐Carrier” synergy th...
Autores principales: | Han, Guochen, Bai, Kaiwen, Yang, Xiaoyu, Sun, Chenhua, Ji, Yi, Zhou, Jianping, Zhang, Huaqing, Ding, Yang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108666/ https://www.ncbi.nlm.nih.gov/pubmed/35307993 http://dx.doi.org/10.1002/advs.202106072 |
Ejemplares similares
-
Amyloid-β and hyperphosphorylated tau synergy drives metabolic decline in preclinical Alzheimer's disease
por: Pascoal, T A, et al.
Publicado: (2017) -
Regional correlation of biochemical measures of amyloid and tau phosphorylation in the brain
por: Horie, Kanta, et al.
Publicado: (2020) -
Disease‐Associated Tau Phosphorylation Hinders Tubulin Assembly within Tau Condensates
por: Savastano, Adriana, et al.
Publicado: (2020) -
Amyloid-beta and phosphorylated tau in post-mortem Alzheimer’s disease retinas
por: den Haan, Jurre, et al.
Publicado: (2018) -
Plasma phosphorylated-tau181 as a predictive biomarker for Alzheimer’s amyloid, tau and FDG PET status
por: Shen, Xue-Ning, et al.
Publicado: (2021)