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The Effects of Free Heme on Functional and Molecular Changes During Ex Vivo Normothermic Machine Perfusion of Human Kidneys

Normothermic machine perfusion (NMP) is a technique of kidney preservation designed to restore cellular metabolism after cold ischemia. Kidneys are perfused with an oxygenated banked red blood cell (RBC) based solution for 1h at 36°C. During NMP, RBCs can become damaged, releasing free heme into the...

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Detalles Bibliográficos
Autores principales:	Hosgood, Sarah A., Elliott, Tegwen R., Jordan, Nina P., Nicholson, Michael L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108696/ https://www.ncbi.nlm.nih.gov/pubmed/35585981 http://dx.doi.org/10.3389/fimmu.2022.849742

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