Monocytes Elicit a Neutrophil-Independent Th1/Th17 Response Upon Immunization With a Mincle-Dependent Glycolipid Adjuvant

Successful subunit vaccination with recombinant proteins requires adjuvants. The glycolipid trehalose-dibehenate (TDB), a synthetic analog of the mycobacterial cord factor, potently induces Th1 and Th17 immune responses and is a candidate adjuvant for human immunization. TDB binds to the C-type lect...

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Detalles Bibliográficos
Autores principales: Desel, Christiane, Murray, Peter J., Lehmann, Christian H. K., Heger, Lukas, Christensen, Dennis, Andersen, Peter, Mack, Matthias, Dudziak, Diana, Lang, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108773/
https://www.ncbi.nlm.nih.gov/pubmed/35585969
http://dx.doi.org/10.3389/fimmu.2022.880474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108773/
https://www.ncbi.nlm.nih.gov/pubmed/35585969
http://dx.doi.org/10.3389/fimmu.2022.880474

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