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Clinical and Radiographic Evaluation of Curcumin as an Obturation Material in Deciduous Teeth: A Randomized Controlled Trial

AIM AND OBJECTIVE: To evaluate the clinical and radiographic success rates of curcumin, curcumin and calcium hydroxide in equal proportions and calcium hydroxide as an obturation material compared to curcumin and calcium hydroxidet (Metapex). MATERIALS AND METHODS: This study included 64 primary mol...

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Autores principales: Bommareddy, Charishma Sai, Ramkumar, Hemalatha, Dakshinamurthy, Senthil, Paulindraraj, Shankar, Jayakaran, Trophimus Gnanabagyan, Shankar, Karthika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Jaypee Brothers Medical Publishers 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108815/
https://www.ncbi.nlm.nih.gov/pubmed/35645494
http://dx.doi.org/10.5005/jp-journals-10005-2128
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author Bommareddy, Charishma Sai
Ramkumar, Hemalatha
Dakshinamurthy, Senthil
Paulindraraj, Shankar
Jayakaran, Trophimus Gnanabagyan
Shankar, Karthika
author_facet Bommareddy, Charishma Sai
Ramkumar, Hemalatha
Dakshinamurthy, Senthil
Paulindraraj, Shankar
Jayakaran, Trophimus Gnanabagyan
Shankar, Karthika
author_sort Bommareddy, Charishma Sai
collection PubMed
description AIM AND OBJECTIVE: To evaluate the clinical and radiographic success rates of curcumin, curcumin and calcium hydroxide in equal proportions and calcium hydroxide as an obturation material compared to curcumin and calcium hydroxidet (Metapex). MATERIALS AND METHODS: This study included 64 primary molars with irreversible pulpitis indicated for single visit pulpectomy. After obtaining informed consent from the parents, all the teeth were randomly allocated to one of four groups. Pulpectomy was performed using rubber dam isolation and was obturated. The samples were categorized into the four groups based on obturation material namely, group A: curcumin with calcium hydroxide in equal proportions, group B: curcumin, group C: calcium hydroxide, and group D: Metapex. Clinical and radiographic outcomes were evaluated at time intervals of 10 days, 1 month, 3 months, and 6 months. Data was subjected to statistical analysis. Chi-square tests were used compare the groups. RESULTS: At the end of 6 months, clinical and radiographic success rates of groups A, B, and C showed 81.3%, 61.5%, and 93.8%, respectively, while group D had 100% success rate. CONCLUSION: Among the four groups, the hierarchy of success rates are as follows: Metapex > calcium hydroxide > curcumin and calcium hydroxide > curcumin. However, various formulations and combinations of curcumin can still be extended with larger sample size. CLINICAL SIGNIFICANCE: Curcumin and calcium hydroxide paste can be used as an obturating material with further follow-up studies. HOW TO CITE THIS ARTICLE: Bommareddy CS, Ramkumar H, Dakshinamurthy S, et al. Clinical and Radiographic Evaluation of Curcumin as an Obturation Material in Deciduous Teeth: A Randomized Controlled Trial. Int J Clin Pediatr Dent 2022;15(S-1):S35-S39.
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spelling pubmed-91088152022-05-27 Clinical and Radiographic Evaluation of Curcumin as an Obturation Material in Deciduous Teeth: A Randomized Controlled Trial Bommareddy, Charishma Sai Ramkumar, Hemalatha Dakshinamurthy, Senthil Paulindraraj, Shankar Jayakaran, Trophimus Gnanabagyan Shankar, Karthika Int J Clin Pediatr Dent Research Article AIM AND OBJECTIVE: To evaluate the clinical and radiographic success rates of curcumin, curcumin and calcium hydroxide in equal proportions and calcium hydroxide as an obturation material compared to curcumin and calcium hydroxidet (Metapex). MATERIALS AND METHODS: This study included 64 primary molars with irreversible pulpitis indicated for single visit pulpectomy. After obtaining informed consent from the parents, all the teeth were randomly allocated to one of four groups. Pulpectomy was performed using rubber dam isolation and was obturated. The samples were categorized into the four groups based on obturation material namely, group A: curcumin with calcium hydroxide in equal proportions, group B: curcumin, group C: calcium hydroxide, and group D: Metapex. Clinical and radiographic outcomes were evaluated at time intervals of 10 days, 1 month, 3 months, and 6 months. Data was subjected to statistical analysis. Chi-square tests were used compare the groups. RESULTS: At the end of 6 months, clinical and radiographic success rates of groups A, B, and C showed 81.3%, 61.5%, and 93.8%, respectively, while group D had 100% success rate. CONCLUSION: Among the four groups, the hierarchy of success rates are as follows: Metapex > calcium hydroxide > curcumin and calcium hydroxide > curcumin. However, various formulations and combinations of curcumin can still be extended with larger sample size. CLINICAL SIGNIFICANCE: Curcumin and calcium hydroxide paste can be used as an obturating material with further follow-up studies. HOW TO CITE THIS ARTICLE: Bommareddy CS, Ramkumar H, Dakshinamurthy S, et al. Clinical and Radiographic Evaluation of Curcumin as an Obturation Material in Deciduous Teeth: A Randomized Controlled Trial. Int J Clin Pediatr Dent 2022;15(S-1):S35-S39. Jaypee Brothers Medical Publishers 2022 /pmc/articles/PMC9108815/ /pubmed/35645494 http://dx.doi.org/10.5005/jp-journals-10005-2128 Text en Copyright © 2022; The Author(s). https://creativecommons.org/licenses/by-nc/4.0/© The Author(s). 2022 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted use, distribution, and non-commercial reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Bommareddy, Charishma Sai
Ramkumar, Hemalatha
Dakshinamurthy, Senthil
Paulindraraj, Shankar
Jayakaran, Trophimus Gnanabagyan
Shankar, Karthika
Clinical and Radiographic Evaluation of Curcumin as an Obturation Material in Deciduous Teeth: A Randomized Controlled Trial
title Clinical and Radiographic Evaluation of Curcumin as an Obturation Material in Deciduous Teeth: A Randomized Controlled Trial
title_full Clinical and Radiographic Evaluation of Curcumin as an Obturation Material in Deciduous Teeth: A Randomized Controlled Trial
title_fullStr Clinical and Radiographic Evaluation of Curcumin as an Obturation Material in Deciduous Teeth: A Randomized Controlled Trial
title_full_unstemmed Clinical and Radiographic Evaluation of Curcumin as an Obturation Material in Deciduous Teeth: A Randomized Controlled Trial
title_short Clinical and Radiographic Evaluation of Curcumin as an Obturation Material in Deciduous Teeth: A Randomized Controlled Trial
title_sort clinical and radiographic evaluation of curcumin as an obturation material in deciduous teeth: a randomized controlled trial
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108815/
https://www.ncbi.nlm.nih.gov/pubmed/35645494
http://dx.doi.org/10.5005/jp-journals-10005-2128
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