Biocompatibility of Chitosan Nanoparticle in Root Canal Sealant with Vero Cell Line

Root canal sealants placed in primary tooth are unique in various characteristics. Chitosan nanoparticles have gained an important milestone in research area due to its biodegradable and its bioavailability nature. Chitosan nanoparticles synthesized by ionic gelation method and studied for its physi...

Descripción completa

Detalles Bibliográficos
Autores principales: Ramar, Kavitha, N, Vivek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Jaypee Brothers Medical Publishers 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108829/
https://www.ncbi.nlm.nih.gov/pubmed/35645493
http://dx.doi.org/10.5005/jp-journals-10005-2133
_version_ 1784708790690512896
author Ramar, Kavitha
N, Vivek
author_facet Ramar, Kavitha
N, Vivek
author_sort Ramar, Kavitha
collection PubMed
description Root canal sealants placed in primary tooth are unique in various characteristics. Chitosan nanoparticles have gained an important milestone in research area due to its biodegradable and its bioavailability nature. Chitosan nanoparticles synthesized by ionic gelation method and studied for its physical characteristics when added with root canal sealant provides a promising result. In this study, biocompatibility nature of Chitosan nanoparticles with Vero cell line was being investigated. Several solution parameters of Chitosan nanoparticles and root canal sealants were investigated to optimize diameter of nanoparticles after being characterized to XRD, SEM, and FTIR. The Chitosan nanoparticles were found to be biocompatible to fibroblasts and on a dose-dependent manner, these can be used in combination with the root canal sealant in primary teeth. How to cite this article: Ramar K, N V. Biocompatibility of Chitosan Nanoparticle in Root Canal Sealant with Vero Cell Line. Int J Clin Pediatr Dent 2022;15(S-1):S57-S62.
format Online
Article
Text
id pubmed-9108829
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Jaypee Brothers Medical Publishers
record_format MEDLINE/PubMed
spelling pubmed-91088292022-05-27 Biocompatibility of Chitosan Nanoparticle in Root Canal Sealant with Vero Cell Line Ramar, Kavitha N, Vivek Int J Clin Pediatr Dent Research Article Root canal sealants placed in primary tooth are unique in various characteristics. Chitosan nanoparticles have gained an important milestone in research area due to its biodegradable and its bioavailability nature. Chitosan nanoparticles synthesized by ionic gelation method and studied for its physical characteristics when added with root canal sealant provides a promising result. In this study, biocompatibility nature of Chitosan nanoparticles with Vero cell line was being investigated. Several solution parameters of Chitosan nanoparticles and root canal sealants were investigated to optimize diameter of nanoparticles after being characterized to XRD, SEM, and FTIR. The Chitosan nanoparticles were found to be biocompatible to fibroblasts and on a dose-dependent manner, these can be used in combination with the root canal sealant in primary teeth. How to cite this article: Ramar K, N V. Biocompatibility of Chitosan Nanoparticle in Root Canal Sealant with Vero Cell Line. Int J Clin Pediatr Dent 2022;15(S-1):S57-S62. Jaypee Brothers Medical Publishers 2022 /pmc/articles/PMC9108829/ /pubmed/35645493 http://dx.doi.org/10.5005/jp-journals-10005-2133 Text en Copyright © 2022; The Author(s). https://creativecommons.org/licenses/by-nc/4.0/© The Author(s). 2022 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted use, distribution, and non-commercial reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Ramar, Kavitha
N, Vivek
Biocompatibility of Chitosan Nanoparticle in Root Canal Sealant with Vero Cell Line
title Biocompatibility of Chitosan Nanoparticle in Root Canal Sealant with Vero Cell Line
title_full Biocompatibility of Chitosan Nanoparticle in Root Canal Sealant with Vero Cell Line
title_fullStr Biocompatibility of Chitosan Nanoparticle in Root Canal Sealant with Vero Cell Line
title_full_unstemmed Biocompatibility of Chitosan Nanoparticle in Root Canal Sealant with Vero Cell Line
title_short Biocompatibility of Chitosan Nanoparticle in Root Canal Sealant with Vero Cell Line
title_sort biocompatibility of chitosan nanoparticle in root canal sealant with vero cell line
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108829/
https://www.ncbi.nlm.nih.gov/pubmed/35645493
http://dx.doi.org/10.5005/jp-journals-10005-2133
work_keys_str_mv AT ramarkavitha biocompatibilityofchitosannanoparticleinrootcanalsealantwithverocellline
AT nvivek biocompatibilityofchitosannanoparticleinrootcanalsealantwithverocellline

Ejemplares similares