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Central pontine myelinolysis in a chronic alcoholic patient with mild hyponatremia: A case report
INTRODUCTION: Central pontine myelinolysis is a type of osmotic demyelination syndrome, which involves damage to parts of brain most commonly pons. The most common causes include rapid correction of hyponatremia but other precipitating factors including alcoholism, diabetes, and chronic liver diseas...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108878/ https://www.ncbi.nlm.nih.gov/pubmed/35585991 http://dx.doi.org/10.1016/j.amsu.2022.103736 |
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author | Dahal, Abhinav Bhattarai, Ayush Mohan Bhattarai, Ashish Mohan Pathak, Bishnu Deep Karki, Abinash Aryal, Egesh |
author_facet | Dahal, Abhinav Bhattarai, Ayush Mohan Bhattarai, Ashish Mohan Pathak, Bishnu Deep Karki, Abinash Aryal, Egesh |
author_sort | Dahal, Abhinav |
collection | PubMed |
description | INTRODUCTION: Central pontine myelinolysis is a type of osmotic demyelination syndrome, which involves damage to parts of brain most commonly pons. The most common causes include rapid correction of hyponatremia but other precipitating factors including alcoholism, diabetes, and chronic liver disease should also be considered. CASE PRESENTATION: We present a case of 44-year-old male with a history of chronic alcohol consumption, who presented in emergency room with complaints of slurring of speech and weakness of both upper and lower limbs. His MRI brain reveals ‘trident-shaped’ appearance with findings of High T2W/FLAIR signal noted in the pons with relative sparing of the periphery and hypo intense on T1W images. He was managed conservatively. CLINICAL DISCUSSION: Proper diagnosis with MRI is needed for early detection so that proper intervention can be made on time. CONCLUSION: CPM can occur in the patient even if they are normonatremic or hyponatremic but can precipitate in Chronic Alcoholic patients. |
format | Online Article Text |
id | pubmed-9108878 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-91088782022-05-17 Central pontine myelinolysis in a chronic alcoholic patient with mild hyponatremia: A case report Dahal, Abhinav Bhattarai, Ayush Mohan Bhattarai, Ashish Mohan Pathak, Bishnu Deep Karki, Abinash Aryal, Egesh Ann Med Surg (Lond) Case Report INTRODUCTION: Central pontine myelinolysis is a type of osmotic demyelination syndrome, which involves damage to parts of brain most commonly pons. The most common causes include rapid correction of hyponatremia but other precipitating factors including alcoholism, diabetes, and chronic liver disease should also be considered. CASE PRESENTATION: We present a case of 44-year-old male with a history of chronic alcohol consumption, who presented in emergency room with complaints of slurring of speech and weakness of both upper and lower limbs. His MRI brain reveals ‘trident-shaped’ appearance with findings of High T2W/FLAIR signal noted in the pons with relative sparing of the periphery and hypo intense on T1W images. He was managed conservatively. CLINICAL DISCUSSION: Proper diagnosis with MRI is needed for early detection so that proper intervention can be made on time. CONCLUSION: CPM can occur in the patient even if they are normonatremic or hyponatremic but can precipitate in Chronic Alcoholic patients. Elsevier 2022-05-07 /pmc/articles/PMC9108878/ /pubmed/35585991 http://dx.doi.org/10.1016/j.amsu.2022.103736 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Dahal, Abhinav Bhattarai, Ayush Mohan Bhattarai, Ashish Mohan Pathak, Bishnu Deep Karki, Abinash Aryal, Egesh Central pontine myelinolysis in a chronic alcoholic patient with mild hyponatremia: A case report |
title | Central pontine myelinolysis in a chronic alcoholic patient with mild hyponatremia: A case report |
title_full | Central pontine myelinolysis in a chronic alcoholic patient with mild hyponatremia: A case report |
title_fullStr | Central pontine myelinolysis in a chronic alcoholic patient with mild hyponatremia: A case report |
title_full_unstemmed | Central pontine myelinolysis in a chronic alcoholic patient with mild hyponatremia: A case report |
title_short | Central pontine myelinolysis in a chronic alcoholic patient with mild hyponatremia: A case report |
title_sort | central pontine myelinolysis in a chronic alcoholic patient with mild hyponatremia: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108878/ https://www.ncbi.nlm.nih.gov/pubmed/35585991 http://dx.doi.org/10.1016/j.amsu.2022.103736 |
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