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Central pontine myelinolysis in a chronic alcoholic patient with mild hyponatremia: A case report

INTRODUCTION: Central pontine myelinolysis is a type of osmotic demyelination syndrome, which involves damage to parts of brain most commonly pons. The most common causes include rapid correction of hyponatremia but other precipitating factors including alcoholism, diabetes, and chronic liver diseas...

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Autores principales: Dahal, Abhinav, Bhattarai, Ayush Mohan, Bhattarai, Ashish Mohan, Pathak, Bishnu Deep, Karki, Abinash, Aryal, Egesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108878/
https://www.ncbi.nlm.nih.gov/pubmed/35585991
http://dx.doi.org/10.1016/j.amsu.2022.103736
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author Dahal, Abhinav
Bhattarai, Ayush Mohan
Bhattarai, Ashish Mohan
Pathak, Bishnu Deep
Karki, Abinash
Aryal, Egesh
author_facet Dahal, Abhinav
Bhattarai, Ayush Mohan
Bhattarai, Ashish Mohan
Pathak, Bishnu Deep
Karki, Abinash
Aryal, Egesh
author_sort Dahal, Abhinav
collection PubMed
description INTRODUCTION: Central pontine myelinolysis is a type of osmotic demyelination syndrome, which involves damage to parts of brain most commonly pons. The most common causes include rapid correction of hyponatremia but other precipitating factors including alcoholism, diabetes, and chronic liver disease should also be considered. CASE PRESENTATION: We present a case of 44-year-old male with a history of chronic alcohol consumption, who presented in emergency room with complaints of slurring of speech and weakness of both upper and lower limbs. His MRI brain reveals ‘trident-shaped’ appearance with findings of High T2W/FLAIR signal noted in the pons with relative sparing of the periphery and hypo intense on T1W images. He was managed conservatively. CLINICAL DISCUSSION: Proper diagnosis with MRI is needed for early detection so that proper intervention can be made on time. CONCLUSION: CPM can occur in the patient even if they are normonatremic or hyponatremic but can precipitate in Chronic Alcoholic patients.
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spelling pubmed-91088782022-05-17 Central pontine myelinolysis in a chronic alcoholic patient with mild hyponatremia: A case report Dahal, Abhinav Bhattarai, Ayush Mohan Bhattarai, Ashish Mohan Pathak, Bishnu Deep Karki, Abinash Aryal, Egesh Ann Med Surg (Lond) Case Report INTRODUCTION: Central pontine myelinolysis is a type of osmotic demyelination syndrome, which involves damage to parts of brain most commonly pons. The most common causes include rapid correction of hyponatremia but other precipitating factors including alcoholism, diabetes, and chronic liver disease should also be considered. CASE PRESENTATION: We present a case of 44-year-old male with a history of chronic alcohol consumption, who presented in emergency room with complaints of slurring of speech and weakness of both upper and lower limbs. His MRI brain reveals ‘trident-shaped’ appearance with findings of High T2W/FLAIR signal noted in the pons with relative sparing of the periphery and hypo intense on T1W images. He was managed conservatively. CLINICAL DISCUSSION: Proper diagnosis with MRI is needed for early detection so that proper intervention can be made on time. CONCLUSION: CPM can occur in the patient even if they are normonatremic or hyponatremic but can precipitate in Chronic Alcoholic patients. Elsevier 2022-05-07 /pmc/articles/PMC9108878/ /pubmed/35585991 http://dx.doi.org/10.1016/j.amsu.2022.103736 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Dahal, Abhinav
Bhattarai, Ayush Mohan
Bhattarai, Ashish Mohan
Pathak, Bishnu Deep
Karki, Abinash
Aryal, Egesh
Central pontine myelinolysis in a chronic alcoholic patient with mild hyponatremia: A case report
title Central pontine myelinolysis in a chronic alcoholic patient with mild hyponatremia: A case report
title_full Central pontine myelinolysis in a chronic alcoholic patient with mild hyponatremia: A case report
title_fullStr Central pontine myelinolysis in a chronic alcoholic patient with mild hyponatremia: A case report
title_full_unstemmed Central pontine myelinolysis in a chronic alcoholic patient with mild hyponatremia: A case report
title_short Central pontine myelinolysis in a chronic alcoholic patient with mild hyponatremia: A case report
title_sort central pontine myelinolysis in a chronic alcoholic patient with mild hyponatremia: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108878/
https://www.ncbi.nlm.nih.gov/pubmed/35585991
http://dx.doi.org/10.1016/j.amsu.2022.103736
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