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Monocytes are the main source of STING-mediated IFN-α production

BACKGROUND: Type I interferon (IFN-I) production by plasmacytoid dendritic cells (pDCs) occurs during viral infection, in response to Toll-like receptor 7 (TLR7) stimulation and is more vigorous in females than in males. Whether this sex bias persists in ageing people is currently unknown. In this s...

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Detalles Bibliográficos
Autores principales: Congy-Jolivet, Nicolas, Cenac, Claire, Dellacasagrande, Jérôme, Puissant-Lubrano, Bénédicte, Apoil, Pol André, Guedj, Kevin, Abbas, Flora, Laffont, Sophie, Sourdet, Sandrine, Guyonnet, Sophie, Nourhashemi, Fati, Guéry, Jean-Charles, Blancher, Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108881/
https://www.ncbi.nlm.nih.gov/pubmed/35561451
http://dx.doi.org/10.1016/j.ebiom.2022.104047