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RNA polymerase I (Pol I) lobe-binding subunit Rpa12.2 promotes RNA cleavage and proofreading

Elongating nuclear RNA polymerases (Pols) frequently pause, backtrack, and are then reactivated by endonucleolytic cleavage. Pol backtracking and RNA cleavage are also crucial for proofreading, which contributes to transcription fidelity. RNA polymerase I (Pol I) of the yeast Saccharomyces cerevisia...

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Detalles Bibliográficos
Autores principales:	Schwank, Katrin, Schmid, Catharina, Fremter, Tobias, Milkereit, Philipp, Griesenbeck, Joachim, Tschochner, Herbert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108883/ https://www.ncbi.nlm.nih.gov/pubmed/35341765 http://dx.doi.org/10.1016/j.jbc.2022.101862

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