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Ectopic Lymphoid Follicle Formation and Human Seasonal Influenza Vaccination Responses Recapitulated in an Organ‐on‐a‐Chip (Adv. Sci. 14/2022)
Organ‐on‐a‐Chip A microfluidic organ‐on‐a‐chip model of the human lymphoid follicle that recapitulates vaccination responses in vitro. Blood‐derived cells self assemble into germinal centers in a matrix gel in the lower channel when nutrient medium is flowed through the upper channel. Antigen‐specif...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109052/ http://dx.doi.org/10.1002/advs.202270090 |
| _version_ | 1784708830387503104 |
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| author | Goyal, Girija Prabhala, Pranav Mahajan, Gautam Bausk, Bruce Gilboa, Tal Xie, Liangxia Zhai, Yunhao Lazarovits, Roey Mansour, Adam Kim, Min Sun Patil, Aditya Curran, Danielle Long, Jaclyn M. Sharma, Sanjay Junaid, Abidemi Cohen, Limor Ferrante, Thomas C. Levy, Oren Prantil‐Baun, Rachelle Walt, David R. Ingber, Donald E. |
| author_facet | Goyal, Girija Prabhala, Pranav Mahajan, Gautam Bausk, Bruce Gilboa, Tal Xie, Liangxia Zhai, Yunhao Lazarovits, Roey Mansour, Adam Kim, Min Sun Patil, Aditya Curran, Danielle Long, Jaclyn M. Sharma, Sanjay Junaid, Abidemi Cohen, Limor Ferrante, Thomas C. Levy, Oren Prantil‐Baun, Rachelle Walt, David R. Ingber, Donald E. |
| author_sort | Goyal, Girija |
| collection | PubMed |
| description | Organ‐on‐a‐Chip A microfluidic organ‐on‐a‐chip model of the human lymphoid follicle that recapitulates vaccination responses in vitro. Blood‐derived cells self assemble into germinal centers in a matrix gel in the lower channel when nutrient medium is flowed through the upper channel. Antigen‐specific antibodies and cytokines are secreted in response to seasonal influenza vaccination that mirror responses observed in patients. More details can be found in article number 2103241 by Donald E. Ingber and co‐workers. [Image: see text] |
| format | Online Article Text |
| id | pubmed-9109052 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2022 |
| publisher | John Wiley and Sons Inc. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-91090522022-05-20 Ectopic Lymphoid Follicle Formation and Human Seasonal Influenza Vaccination Responses Recapitulated in an Organ‐on‐a‐Chip (Adv. Sci. 14/2022) Goyal, Girija Prabhala, Pranav Mahajan, Gautam Bausk, Bruce Gilboa, Tal Xie, Liangxia Zhai, Yunhao Lazarovits, Roey Mansour, Adam Kim, Min Sun Patil, Aditya Curran, Danielle Long, Jaclyn M. Sharma, Sanjay Junaid, Abidemi Cohen, Limor Ferrante, Thomas C. Levy, Oren Prantil‐Baun, Rachelle Walt, David R. Ingber, Donald E. Adv Sci (Weinh) Frontispiece Organ‐on‐a‐Chip A microfluidic organ‐on‐a‐chip model of the human lymphoid follicle that recapitulates vaccination responses in vitro. Blood‐derived cells self assemble into germinal centers in a matrix gel in the lower channel when nutrient medium is flowed through the upper channel. Antigen‐specific antibodies and cytokines are secreted in response to seasonal influenza vaccination that mirror responses observed in patients. More details can be found in article number 2103241 by Donald E. Ingber and co‐workers. [Image: see text] John Wiley and Sons Inc. 2022-05-16 /pmc/articles/PMC9109052/ http://dx.doi.org/10.1002/advs.202270090 Text en © 2022 Wiley‐VCH GmbH https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
| spellingShingle | Frontispiece Goyal, Girija Prabhala, Pranav Mahajan, Gautam Bausk, Bruce Gilboa, Tal Xie, Liangxia Zhai, Yunhao Lazarovits, Roey Mansour, Adam Kim, Min Sun Patil, Aditya Curran, Danielle Long, Jaclyn M. Sharma, Sanjay Junaid, Abidemi Cohen, Limor Ferrante, Thomas C. Levy, Oren Prantil‐Baun, Rachelle Walt, David R. Ingber, Donald E. Ectopic Lymphoid Follicle Formation and Human Seasonal Influenza Vaccination Responses Recapitulated in an Organ‐on‐a‐Chip (Adv. Sci. 14/2022) |
| title | Ectopic Lymphoid Follicle Formation and Human Seasonal Influenza Vaccination Responses Recapitulated in an Organ‐on‐a‐Chip (Adv. Sci. 14/2022) |
| title_full | Ectopic Lymphoid Follicle Formation and Human Seasonal Influenza Vaccination Responses Recapitulated in an Organ‐on‐a‐Chip (Adv. Sci. 14/2022) |
| title_fullStr | Ectopic Lymphoid Follicle Formation and Human Seasonal Influenza Vaccination Responses Recapitulated in an Organ‐on‐a‐Chip (Adv. Sci. 14/2022) |
| title_full_unstemmed | Ectopic Lymphoid Follicle Formation and Human Seasonal Influenza Vaccination Responses Recapitulated in an Organ‐on‐a‐Chip (Adv. Sci. 14/2022) |
| title_short | Ectopic Lymphoid Follicle Formation and Human Seasonal Influenza Vaccination Responses Recapitulated in an Organ‐on‐a‐Chip (Adv. Sci. 14/2022) |
| title_sort | ectopic lymphoid follicle formation and human seasonal influenza vaccination responses recapitulated in an organ‐on‐a‐chip (adv. sci. 14/2022) |
| topic | Frontispiece |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109052/ http://dx.doi.org/10.1002/advs.202270090 |
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