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Clinical significance of plasma-free amino acids and tryptophan metabolites in patients with non-small cell lung cancer receiving PD-1 inhibitor: a pilot cohort study for developing a prognostic multivariate model
BACKGROUND: Amino acid metabolism is essential for tumor cell proliferation and regulation of immune cell function. However, the clinical significance of free amino acids (plasma-free amino acids (PFAAs)) and tryptophan-related metabolites in plasma has not been fully understood in patients with non...
Autores principales: | Azuma, Koichi, Xiang, Huihui, Tagami, Tomoyuki, Kasajima, Rika, Kato, Yumiko, Karakawa, Sachise, Kikuchi, Shinya, Imaizumi, Akira, Matsuo, Norikazu, Ishii, Hidenobu, Tokito, Takaaki, Kawahara, Akihiko, Murotani, Kenta, Sasada, Tetsuro, Miyagi, Yohei, Hoshino, Tomoaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109096/ https://www.ncbi.nlm.nih.gov/pubmed/35569917 http://dx.doi.org/10.1136/jitc-2021-004420 |
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