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Famotidine activates the vagus nerve inflammatory reflex to attenuate cytokine storm
BACKGROUND: Severe COVID-19 is characterized by pro-inflammatory cytokine release syndrome (cytokine storm) which causes high morbidity and mortality. Recent observational and clinical studies suggest famotidine, a histamine 2 receptor (H2R) antagonist widely used to treat gastroesophageal reflux di...
Autores principales: | Yang, Huan, George, Sam J., Thompson, Dane A., Silverman, Harold A., Tsaava, Téa, Tynan, Aisling, Pavlov, Valentin A., Chang, Eric H., Andersson, Ulf, Brines, Michael, Chavan, Sangeeta S., Tracey, Kevin J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109205/ https://www.ncbi.nlm.nih.gov/pubmed/35578169 http://dx.doi.org/10.1186/s10020-022-00483-8 |
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