Famotidine activates the vagus nerve inflammatory reflex to attenuate cytokine storm

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BACKGROUND: Severe COVID-19 is characterized by pro-inflammatory cytokine release syndrome (cytokine storm) which causes high morbidity and mortality. Recent observational and clinical studies suggest famotidine, a histamine 2 receptor (H2R) antagonist widely used to treat gastroesophageal reflux di...

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Detalles Bibliográficos
Autores principales: Yang, Huan, George, Sam J., Thompson, Dane A., Silverman, Harold A., Tsaava, Téa, Tynan, Aisling, Pavlov, Valentin A., Chang, Eric H., Andersson, Ulf, Brines, Michael, Chavan, Sangeeta S., Tracey, Kevin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109205/
https://www.ncbi.nlm.nih.gov/pubmed/35578169
http://dx.doi.org/10.1186/s10020-022-00483-8
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