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Gemella haemolysans: Rare case of automatic implantable cardioverter-defibrillator (AICD) lead infection

We present a rare case of Gemella haemolysans automated implantable cardioverter defibrillator (AICD) lead infection. Gemella species are catalase-negative, facultative anaerobic, Gram-positive cocci which are found in normal human oral flora. Gemella are often incorrectly identified on routine Gram...

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Autores principales: Kriege, Kevin, Wilson, Brycen, Tate, Joshua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109277/
https://www.ncbi.nlm.nih.gov/pubmed/35585852
http://dx.doi.org/10.1177/2050313X221099367
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author Kriege, Kevin
Wilson, Brycen
Tate, Joshua
author_facet Kriege, Kevin
Wilson, Brycen
Tate, Joshua
author_sort Kriege, Kevin
collection PubMed
description We present a rare case of Gemella haemolysans automated implantable cardioverter defibrillator (AICD) lead infection. Gemella species are catalase-negative, facultative anaerobic, Gram-positive cocci which are found in normal human oral flora. Gemella are often incorrectly identified on routine Gram stain and culture, requiring advanced techniques such as PCR. Gemella has been shown to be a rare cause infective endocarditis in case reports; however, there has not been a report of an isolated AICD lead infection. AICD infections with gram positive organisms other than Staphylococcus species has been associated with more aggressive infections and higher mortality. Standard treatment for Gemella consists of β-lactam inhibitors and aminoglycosides. In this case, we present an alternative antibiotic treatment with vancomycin and ceftriaxone. A case series for Gemella haemolysans endocarditis, without lead infection, reported the use of vancomycin and ceftriaxone with good results. This approach is similar to methicillin-resistant staphylococcus aureus (MRSA) bacteremia salvage therapy. In addition, this case highlights the importance of culture and sensitivity in the selection of antibiotics, particularly avoiding nephrotoxic drugs when possible.
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spelling pubmed-91092772022-05-17 Gemella haemolysans: Rare case of automatic implantable cardioverter-defibrillator (AICD) lead infection Kriege, Kevin Wilson, Brycen Tate, Joshua SAGE Open Med Case Rep Case Report We present a rare case of Gemella haemolysans automated implantable cardioverter defibrillator (AICD) lead infection. Gemella species are catalase-negative, facultative anaerobic, Gram-positive cocci which are found in normal human oral flora. Gemella are often incorrectly identified on routine Gram stain and culture, requiring advanced techniques such as PCR. Gemella has been shown to be a rare cause infective endocarditis in case reports; however, there has not been a report of an isolated AICD lead infection. AICD infections with gram positive organisms other than Staphylococcus species has been associated with more aggressive infections and higher mortality. Standard treatment for Gemella consists of β-lactam inhibitors and aminoglycosides. In this case, we present an alternative antibiotic treatment with vancomycin and ceftriaxone. A case series for Gemella haemolysans endocarditis, without lead infection, reported the use of vancomycin and ceftriaxone with good results. This approach is similar to methicillin-resistant staphylococcus aureus (MRSA) bacteremia salvage therapy. In addition, this case highlights the importance of culture and sensitivity in the selection of antibiotics, particularly avoiding nephrotoxic drugs when possible. SAGE Publications 2022-05-13 /pmc/articles/PMC9109277/ /pubmed/35585852 http://dx.doi.org/10.1177/2050313X221099367 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Kriege, Kevin
Wilson, Brycen
Tate, Joshua
Gemella haemolysans: Rare case of automatic implantable cardioverter-defibrillator (AICD) lead infection
title Gemella haemolysans: Rare case of automatic implantable cardioverter-defibrillator (AICD) lead infection
title_full Gemella haemolysans: Rare case of automatic implantable cardioverter-defibrillator (AICD) lead infection
title_fullStr Gemella haemolysans: Rare case of automatic implantable cardioverter-defibrillator (AICD) lead infection
title_full_unstemmed Gemella haemolysans: Rare case of automatic implantable cardioverter-defibrillator (AICD) lead infection
title_short Gemella haemolysans: Rare case of automatic implantable cardioverter-defibrillator (AICD) lead infection
title_sort gemella haemolysans: rare case of automatic implantable cardioverter-defibrillator (aicd) lead infection
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109277/
https://www.ncbi.nlm.nih.gov/pubmed/35585852
http://dx.doi.org/10.1177/2050313X221099367
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