MiR-129-5p exerts Wnt signaling-dependent tumor-suppressive functions in hepatocellular carcinoma by directly targeting hepatoma-derived growth factor HDGF

BACKGROUND: In hepatocellular carcinoma (HCC), histone deacetylases (HDACs) are frequently overexpressed. This results in chromatin compaction and silencing of tumor-relevant genes and microRNAs. Modulation of microRNA expression is a potential treatment option for HCC. Therefore, we aimed to charac...

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Detalles Bibliográficos
Autores principales: Huge, Nicole, Reinkens, Thea, Buurman, Reena, Sandbothe, Maria, Bergmann, Anke, Wallaschek, Hannah, Vajen, Beate, Stalke, Amelie, Decker, Melanie, Eilers, Marlies, Schäffer, Vera, Dittrich-Breiholz, Oliver, Gürlevik, Engin, Kühnel, Florian, Schlegelberger, Brigitte, Illig, Thomas, Skawran, Britta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109340/
https://www.ncbi.nlm.nih.gov/pubmed/35578240
http://dx.doi.org/10.1186/s12935-022-02582-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109340/
https://www.ncbi.nlm.nih.gov/pubmed/35578240
http://dx.doi.org/10.1186/s12935-022-02582-2

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